Leonardo Salviati Selected Research

Collagen

1/2018

Drug Repurposing for Duchenne Muscular Dystrophy: The Monoamine Oxidase B Inhibitor Safinamide Ameliorates the Pathological Phenotype in mdx Mice and in Myogenic Cultures From DMD Patients.

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Leonardo Salviati Research Topics

Disease

15	Coenzyme Q10 Deficiency 02/2024 - 02/2006
10	Mitochondrial Diseases (Mitochondrial Disease) 09/2021 - 01/2008
5	Glycogen Storage Disease Type II (Pompe's Disease) 12/2023 - 10/2011
4	Friedreich Ataxia (Friedreich's Ataxia) 01/2024 - 01/2018
4	Cardiomyopathies (Cardiomyopathy) 03/2023 - 01/2012
4	Muscular Diseases (Myopathy) 01/2022 - 01/2010
4	Ataxia (Dyssynergia) 09/2021 - 03/2013
4	Gyrate Atrophy 01/2021 - 01/2013
4	Brain Diseases (Brain Disorder) 08/2016 - 01/2013
4	Cytochrome-c Oxidase Deficiency 04/2012 - 02/2003
3	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023 - 01/2021
3	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2023 - 06/2017
3	Mitochondrial Myopathies (Mitochondrial Myopathy) 09/2019 - 11/2002
3	Hyperammonemia 01/2016 - 07/2007
3	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2015 - 05/2011
3	Argininosuccinic Aciduria 05/2012 - 07/2007
2	Mucopolysaccharidosis I (Hurler Syndrome) 12/2023 - 11/2020
2	Gaucher Disease (Gaucher's Disease) 12/2023 - 01/2023
2	X-Linked Bulbo-Spinal Atrophy 01/2023 - 01/2017
2	Liver Diseases (Liver Disease) 01/2023 - 09/2019
2	Hypertension (High Blood Pressure) 01/2022 - 05/2012
2	Multiple Acyl Coenzyme A Dehydrogenase Deficiency 05/2020 - 01/2015
2	Atrophy 01/2016 - 02/2006
2	Cataract (Cataracts) 07/2013 - 01/2012
1	Thoracic Aortic Aneurysm 03/2024
1	Burkitt Lymphoma (Burkitt's Lymphoma) 02/2024
1	Rigor Mortis 02/2024
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 12/2023
1	Fabry Disease (Fabry's Disease) 12/2023
1	Peroxisomal Disorders (Peroxisomal Disorder) 11/2023
1	Seizures (Absence Seizure) 11/2023
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 03/2023
1	Dystonic Disorders (Writer's Cramp) 01/2023
1	Pathologic Processes 01/2023
1	Keratoacanthoma familial 01/2023
1	Parkinsonian Disorders (Parkinsonism) 01/2023
1	Loeys-Dietz Syndrome 01/2023
1	Sensorineural Hearing Loss 09/2022
1	Muscle Hypotonia (Hypotonia) 09/2022
1	Pseudohypoaldosteronism 01/2022
1	Hyperkalemia 01/2022
1	Frontotemporal Dementia (Semantic Dementia) 01/2022
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022
1	Acidosis 01/2022
1	COVID-19 09/2021
1	Neurodevelopmental Disorders 09/2021
1	Blindness (Hysterical Blindness) 01/2021
1	Iron Overload 01/2021
1	Hemolysis 01/2021
1	Anemia 01/2021
1	Thalassemia 01/2021

Drug/Important Bio-Agent (IBA)

17	coenzyme Q10 (CoQ10)IBA 02/2024 - 02/2006
7	EnzymesIBA 12/2023 - 10/2011
6	Proteins (Proteins, Gene)FDA Link 01/2024 - 12/2014
5	Mitochondrial DNA (mtDNA)IBA 09/2022 - 11/2002
5	ubiquinone 6IBA 01/2019 - 05/2011
3	FrataxinIBA 01/2024 - 01/2021
3	OrnithineIBA 01/2021 - 01/2013
3	Transaminases (Aminotransferases)IBA 01/2021 - 01/2013
3	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 07/2009 - 02/2003
2	DNA (Deoxyribonucleic Acid)IBA 02/2024 - 07/2007
2	polyglutamineIBA 01/2023 - 01/2017
2	Androgen Receptors (Androgen Receptor)IBA 01/2023 - 01/2017
2	UbiquinoneIBA 01/2021 - 07/2008
2	Ornithine-Oxo-Acid Transaminase (Ornithine Aminotransferase)IBA 01/2021 - 01/2021
2	IronIBA 01/2021 - 12/2014
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2018
2	Retinaldehyde (Retinal)IBA 01/2021 - 12/2020
2	Oxidoreductases (Dehydrogenase)IBA 05/2020 - 03/2016
2	Fatty Acids (Saturated Fatty Acids)IBA 05/2020 - 09/2019
2	Mitochondrial Proteins (Mitochondrial Protein)IBA 09/2019 - 06/2017
2	AntioxidantsIBA 01/2018 - 10/2011
2	Coenzymes (Enzyme Cofactors)IBA 01/2018 - 05/2011
2	CopperIBA 12/2014 - 04/2012
2	Argininosuccinate LyaseIBA 10/2009 - 07/2007
1	1,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranose (TAAD)IBA 03/2024
1	Rituximab (Mabthera)FDA Link 02/2024
1	Biomarkers (Surrogate Marker)IBA 12/2023
1	Mitogen-Activated Protein KinasesIBA 11/2023
1	Sirolimus (Rapamycin)FDA Link 11/2023
1	ubiquinone 7IBA 10/2023
1	AntibodiesIBA 03/2023
1	human GAA protein (Myozyme)FDA Link 03/2023
1	LigandsIBA 01/2023
1	AndrogensIBA 01/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2023
1	Transforming Growth Factor-beta Type I ReceptorIBA 01/2023
1	GlucosidasesIBA 12/2022
1	AcidsIBA 12/2022
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 09/2022
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2022
1	ReninIBA 01/2022
1	SaltsIBA 01/2022
1	mitapivatIBA 01/2021

Therapy/Procedure

5	Enzyme Replacement Therapy 03/2023 - 12/2010
5	Therapeutics 09/2021 - 05/2012
2	Aftercare (After-Treatment) 02/2024 - 03/2023
1	Immunomodulation 03/2023
1	Deep Brain Stimulation 01/2023
1	Castration 01/2023